For coupling the Capillary Electrophoresis to a Mass Spectrometry‭, ‬Prince Technologies offers the EMASS-II ion source‭.‬

The PrinCE Next EMASS-II ion source incorporates an EOF driven sheath liquid flow electrospray emitter technology‭. ‬In this novel‭ ‬sheath-flow CE-MS interface design‭; ‬sheath liquid is supplied through a vial comprising an electrode‭. ‬The vial is in liquid communication with the electrospray emitter interior through a tee‭. ‬When the electrode is connected to an external high voltage power supply‭, ‬electroosmotic flow of the sheath liquid is generated from the borosilicate glass emitter surface‭. ‬The sheath liquid‭ ‬flows across the outlet of the separation capillary‭, ‬where it entrains the analyte liquid prior to exiting through the opening at the electrospray emitter tip‭, ‬producing a nanospray generated by electrokinetic flow of the sheath liquid‭, ‬thus minimizing dilution of the CE effluent‭. ‬Compared with a typical sheath-flow CE-MS interface‭, ‬this innovative design results in significant increase in sensitivity and robustness‭.‬